Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
SSO0010X-pro aminopeptidase; Proteases; Belongs to the peptidase M24B family. (351 aa)    
Predicted Functional Partners:
map
Methionine aminopeptidase 2; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
 
  
 0.652
SSO2374
Conserved hypothetical protein; MJ0444.
      0.611
SSO0009
Deacetylase, putative; Histone deacetylase family; Amino Acid Biosynthesis.
       0.588
hisS
Histidyl-tRNA synthetase (hisS); Translation, Aminoacyl tRNA synthetases; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.586
SSO0011
Predicted membrane protein conserved in archaea.
  
    0.518
SSO5023
Hypothetical protein.
       0.472
pdhD-3
Dihydrolipoamide dehydrogenase (pdhD-3); Highest hit with Thermoplasma; Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 
 0.434
pdhD-1
Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
 
 
 0.430
nadE
NH(3+) dependent NAD(+) synthetase (nadE); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
 
    0.427
bcp-2
Peroxiredoxin, bacterioferritin comigratory protein homolog (bcp-2); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
 
 0.421
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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