node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SSO2171 | adkA | SSO2171 | SSO0694 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Adenylate kinase (adkA); Purines. | 0.900 |
SSO2171 | ndk | SSO2171 | SSO0230 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.975 |
SSO2171 | nrd | SSO2171 | SSO0929 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.900 |
SSO2171 | pyK | SSO2171 | SSO0981 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Pyruvate kinase (pyK); Energy Metabolism, Glycolysis; Belongs to the pyruvate kinase family. | 0.900 |
SSO2171 | thiL | SSO2171 | SSO0237 | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | Thiamine monophosphate kinase, putative (thiL); Cofactor Biosynthesis, Thiamine. | 0.900 |
adkA | SSO2171 | SSO0694 | SSO2171 | Adenylate kinase (adkA); Purines. | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.900 |
adkA | ndk | SSO0694 | SSO0230 | Adenylate kinase (adkA); Purines. | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.900 |
adkA | nrd | SSO0694 | SSO0929 | Adenylate kinase (adkA); Purines. | Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.915 |
adkA | purB | SSO0694 | SSO0240 | Adenylate kinase (adkA); Purines. | Adenylosuccinate lyase (adenylosuccinase)(ASL) (purB); Purines; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.916 |
adkA | pyK | SSO0694 | SSO0981 | Adenylate kinase (adkA); Purines. | Pyruvate kinase (pyK); Energy Metabolism, Glycolysis; Belongs to the pyruvate kinase family. | 0.919 |
adkA | rpl18AB | SSO0694 | SSO0699 | Adenylate kinase (adkA); Purines. | LSU ribosomal protein L18AB (rpl18AB); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. | 0.856 |
adkA | rpl30AB | SSO0694 | SSO0697 | Adenylate kinase (adkA); Purines. | LSU ribosomal protein L30AB (rpl30AB); Translation, Ribosomal Proteins. | 0.855 |
adkA | rpl34E | SSO0694 | SSO6374 | Adenylate kinase (adkA); Purines. | LSU ribosomal protein L34E (rpl34E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eL34 family. | 0.860 |
adkA | secY | SSO0694 | SSO0695 | Adenylate kinase (adkA); Purines. | Preprotein translocase secY subunit (secY); The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.884 |
adkA | thiL | SSO0694 | SSO0237 | Adenylate kinase (adkA); Purines. | Thiamine monophosphate kinase, putative (thiL); Cofactor Biosynthesis, Thiamine. | 0.900 |
ndk | SSO2171 | SSO0230 | SSO2171 | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Conserved hypothetical protein; Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency; Belongs to the THEP1 NTPase family. | 0.975 |
ndk | adkA | SSO0230 | SSO0694 | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Adenylate kinase (adkA); Purines. | 0.900 |
ndk | nrd | SSO0230 | SSO0929 | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Ribonucleotide reductase (nrd); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.938 |
ndk | purB | SSO0230 | SSO0240 | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Adenylosuccinate lyase (adenylosuccinase)(ASL) (purB); Purines; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.440 |
ndk | pyK | SSO0230 | SSO0981 | Nucleoside diphosphate kinase (NDP kinase) (ndk); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Pyruvate kinase (pyK); Energy Metabolism, Glycolysis; Belongs to the pyruvate kinase family. | 0.914 |