STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSO1152Conserved hypothetical protein. (409 aa)    
Predicted Functional Partners:
SSO1151
Strong homology to hypothetical protein MTH856.
 
   
 0.980
tldE
Zn-dependent protease, tldE protein homolog, putative (tldE); Proteases.
  
   
 0.838
tldD
Zn-dependent protease, tldD protein homolog, putative (tldD); Zinc metalloprotease. Able to degrade azocasein in vitro.
 
   
0.684
topR-1
Reverse gyrase (topR-1); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity). Its activity is inhibited by the DNA- binding protein 7d (Sso7d), suggesting that the Sso7d activity might counteract the overwinding effect of reverse gyrase. In the C-terminal section; belongs [...]
  
   
 0.612
topR-2
Reverse gyrase (topR-2); Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
   
 0.602
acd-1
Acyl-CoA dehydrogenase (acd-1); Lipid metabolism.
       0.554
SSO1154
Monoamine oxidase regulatory protein; Uncategorized.
       0.554
SSO1150
Hypothetical protein.
       0.483
SSO0195
Membrane conserved hypothetical protein; Putative fibronectin-binding protein. Similarity with PAB1903, PH1465, APE1611, MTH1907, Ta1418, MJ1625, AF2038; Cell Envelope, Membranes.
   
    0.455
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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