STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvC-2Ketol-acid reductoisomerase (ilvC-2); Amino Acid Biosynthesis, Pyruvate; Belongs to the ketol-acid reductoisomerase family. (333 aa)    
Predicted Functional Partners:
ilvD
Dihydroxy-acid dehydratase (ilvD); Amino Acid Biosynthesis; Belongs to the IlvD/Edd family.
 
 
 0.948
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.861
proC
Pyrroline-5-carboxylate reductase (P5CR) (P5C reductase) (proC); Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
     
 0.859
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
  
 0.859
leuB
3-isopropylmalate dehydrogenase (leuB); Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity); Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
  
 0.856
ilvB-2
Acetolactate synthase large subunit homolog (ilvB-2); Amino Acid Biosynthesis, Pyruvate.
 
 
 0.840
ilvB-4
Acetolactate synthase large subunit homolog (ilvB-4); Amino Acid Biosynthesis, Pyruvate; Belongs to the TPP enzyme family.
 
 
 0.810
ilvB-1
Acetolactate synthase large subunit homolog (ilvB-1); Amino Acid Biosynthesis, Pyruvate.
 
 
 0.805
ilvB-6
Acetolactate synthase large subunit homolog (ilvB-6); Amino Acid Biosynthesis, Pyruvate.
 
 
 0.795
leuA-1
2-isopropylmalate synthase, putative (leuA-1); Amino Acid Biosynthesis, Pyruvate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 0.761
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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