Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
msrPeptide methionine sulfoxide reductase (msr); Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (177 aa)    
Predicted Functional Partners:
asd-1
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (asd-1); Amino Acid Biosynthesis, Aspartate.
     
 0.851
SSO0192
Glutaredoxin related protein; Energy Metabolism.
   
 0.849
trxA-1
Thioredoxin (trxA-1); Close hits to Eukaryotic version; Energy Metabolism, Electron transport.
   
 0.849
SSO1120
Glutaredoxin related protein; Some similarity with protein disulfide Oxidoreductase [P. furiosus]; Energy Metabolism.
   
 0.849
trxA-2
Thioredoxin (trxA-2); Energy Metabolism, Electron transport.
   
 0.849
argF
Ornithine carbamoyltransferase (argF); Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
      0.721
cobB
Transcriptional regulatory protein, Sir2 protein homolog; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
      0.632
metB
O-succinylhomoserine (thiol)-lyase (cystathionine gamma-synthase) (metB); Amino Acid Biosynthesis.
  
 
 0.574
tatC
tatC protein (tatC); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
     
 0.554
tatC-like
tatC-like protein, putative (tatC-like); Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
     
 0.554
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
Server load: low (12%) [HD]