Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SSO2126L-lactate permease; Transport, Cell membrane transport. (530 aa)    
Predicted Functional Partners:
SSO2127
Transport protein, permease; Transport, Cell membrane transport.
 
   
 0.881
fni
FMN-dependent dehydrogenase, conserved hypothetical; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
  
  
 0.879
sqdB-2
L-lactate dehydrogenase (sqdB); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
 
  
 0.732
SSO3130
Iron-sulfur protein, conserved putative; Energy Metabolism.
 
   
 0.662
porA-1
Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-1); Energy Metabolism.
     
 0.594
porA-like
Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-like); Energy Metabolism.
     
 0.594
porA-2
Pyruvate synthase alpha chain (Pyruvic-ferredoxin oxidoreductase alpha chain) (porA-2); Energy Metabolism.
     
 0.594
lysM
Transcriptional regulator; In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha-aminoadipate (AAA) pathway.
     
 0.539
SSO0720
Hypothetical protein.
      
 0.532
SSO0606
Transcriptional regulator, putative; Belongs to ASNC family; Transcription, RNA polymerase and transcription factors.
     
 0.472
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
Server load: low (10%) [HD]