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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glpK-2Glycerol kinase (glpK-2); Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (499 aa)    
Predicted Functional Partners:
pan
AAA family ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome as [...]
 
 0.941
glpA
Glycerol-3-phosphate dehydrogenase chain A (glpA); Energy Metabolism.
 
 0.940
SSO0111
Hypothetical protein.
   
 0.938
SSO1601
First ORF in transposon ISC1229; High hits with: bacterial glycerol uptake facilitator protein, and with eukaryal aquaporin.
  
 
 0.905
rpl40E
LSU ribosomal protein L40E (rpl40E); Translation, Ribosomal Proteins; Belongs to the eukaryotic ribosomal protein eL40 family.
    
 0.888
psmB1
Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.883
psmA
Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.883
psmB2
Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
   
 0.883
SSO2612
HtrA like serine protease (periplasmic); Proteases.
   
 0.848
gltA
Citrate synthase; Energy Metabolism; Belongs to the citrate synthase family.
  
  
 0.837
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.