Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SSO2156Endonuclease IV related protein; Replication and Repair. (283 aa)    
Predicted Functional Partners:
SSO2157
Conserved hypothetical protein; Catalyzes the dephosphorylation of 2-phosphoglycolate.
       0.931
ntH-1
DNA endonuclease III, probable (ntH-1); Replication and Repair.
 
 
 0.924
Xth
Exodeoxyribonuclease; Replication and Repair.
   
 
 0.911
eiF4A
RNA helicase (ATP dependent)/eIF4A (eiF4A); A structure-specific endonuclease, cleaves 5' of ds/ssDNA interfaces in 3' flap structures, although it also cuts bubble, Y-DNA structures and mobile and immobile Holliday junctions. Cuts preferentially after pyrimidines, may continue to progressively cleave substrate upstream of the initial cleavage, at least in vitro. May be involved in nucleotide excision repair.
   
 
 0.811
SSO2155
Hypothetical protein.
       0.768
rad2
DNA repair endo/exonuclease FEN-1 (RAD2) (rad2); Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base exci [...]
 
 
 0.696
dpo3
DNA polymerase III (DNA polymerase B3) (pfu polymerase). (dpo3); Replication and Repair.
 
 
 
 0.668
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, putataive (pgsA); Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn- glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3- phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.
     
 0.668
sod
Superoxide dismutase [Fe] (sod); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  
  
 0.658
ape2
Tricorn protease interacting factor F2; Preferentially acts as a leucyl-aminopeptidase, although it also has activity against other substrates.
  
  
 0.657
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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