Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
idhIsocitrate dehydrogenase, probable (idh); Energy Metabolism, Tri-Carboxylic Acid Cycle. (413 aa)    
Predicted Functional Partners:
AcnA
Aconitate hydratase; Energy Metabolism, Tri-Carboxylic Acid Cycle.
  
 0.997
gltA
Citrate synthase; Energy Metabolism; Belongs to the citrate synthase family.
 
 0.992
sqdB-2
L-lactate dehydrogenase (sqdB); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.988
sucC
Succinyl-CoA synthetase, beta subunit (sucC); Energy Metabolism.
  
 0.963
SSO2815
2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.
  
 
 0.917
SSO2816
2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism.
    
 0.917
gdhA-1
NAD specific glutamate dehydrogenase (gdhA-1); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.915
gdhA-2
NAD specific glutamate dehydrogenase (gdhA-2); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.915
gdhA-3
NAD specific glutamate dehydrogenase (gdhA-3); Amino Acid Biosynthesis, Glutamate; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.915
sdhB
Succinate dehydrogenase subunit B (sdhB); Iron-sulfur subunit B; Energy Metabolism, Electron transport.
  
 
 0.914
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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