Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
czcDCation-efflux system membrane protein czcD homolog; Transport. (271 aa)    
Predicted Functional Partners:
merA
Mercuric reductase (Hg(II) reductase) (merA); Cellular Processes, Detoxification; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.860
trxB-3
Thioredoxin reductase (trxB-3); Pyrimidines.
 
   
 0.792
SSO3073
Conserved hypothetical protein.
  
 0.737
atpI
ATP synthase subunit 1 (atpI); Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.678
SSO2228
Transport protein, hypothetical; Putative Co/Zn/Cd cation transporter. Some similarity with aq_1073, aq_2073; Transport.
  
 
 0.573
pacS
Cation transporting ATPase (pacS); Transport.
 
  
 0.509
pdhD-1
Dihydrolipoamide dehydrogenase (pdhD-1); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.487
pdhD-2
Dihydrolipoamide dehydrogenase (pdhD-2); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.479
pdhD-4
Dihydrolipoamide dehydrogenase (pdhD-4); Energy Metabolism, Dehydrogenases; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
 0.477
SSO3250
Conserved hypothetical protein.
 
 
 0.477
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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