Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mcmA1Methylmalonyl-CoA mutase, alpha-subunit, chain A (mcmA1); Highly conserved with Pyrococcus and Archaeoglobus; Cellular Processes, Detoxification. (561 aa)    
Predicted Functional Partners:
mcmA2
Methylmalonyl-CoA mutase, alpha-subunit, chain B (mcmA2); Cellular Processes, Detoxification.
 0.999
MeaB
Conserved hypothetical protein; Putative transport system kinase, argK family protein.
 
 0.996
Mce
Lactoylglutathione lyase (glyoxalase I), putative; Energy Metabolism.
 
  
 0.989
sucC
Succinyl-CoA synthetase, beta subunit (sucC); Energy Metabolism.
  
 
 0.935
sucD
Succinyl-CoA synthetase, alpha subunit (sucD); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.929
SSO2815
2-oxoacid--ferredoxin oxidoreductase, alpha chain; Energy Metabolism.
    
 0.913
SSO2816
2-oxoacid--ferredoxin oxidoreductase, beta chain; Energy Metabolism.
    
 0.911
asd-2
Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (asd-2); Amino Acid Biosynthesis, Aspartate.
    
 0.908
sqdB-2
L-lactate dehydrogenase (sqdB); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
    
 0.841
gltA
Citrate synthase; Energy Metabolism; Belongs to the citrate synthase family.
    
 0.837
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.