STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkK-4Medium-chain-fatty-acid--CoA ligase (alkK-4); Lipid metabolism. (537 aa)    
Predicted Functional Partners:
rpl6AB
LSU ribosomal protein L6AB (rpl6AB); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.838
hdb-2
3-hydroxyacyl-CoA dehydrogenase (hdb-2); Lipid metabolism.
 
  
 0.835
acaB-9
Acetyl-CoA c-acetyltransferase (acetoacetyl-CoA thiolase) (acaB-9); Lipid metabolism.
  
  
 0.815
rpl2AB
LSU ribosomal protein L2AB (rpl2AB); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.742
rpl3AB
LSU ribosomal protein L3AB (rpl3AB); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 
 0.738
sod
Superoxide dismutase [Fe] (sod); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
  
 
 0.736
acd-6
Acyl-CoA dehydrogenase (acd-6); Lipid metabolism.
 
  
 0.736
SSO2872
Conserved hypothetical protein.
  
  
 0.735
rpl13AB
LSU ribosomal protein L13AB (rpl13AB); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.723
hdb-1
3-hydroxyacyl-CoA dehydrogenase (hdb-1); Lipid metabolism.
 
 
 0.721
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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