STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nop10Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (56 aa)    
Predicted Functional Partners:
rpl7AE
LSU ribosomal protein L7AE (rpl7AE); Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs; Belongs to the eukaryotic ribosomal protein eL8 family.
  
 0.999
truB
tRNA pseudouridine synthase subunit B (truB); Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 0.999
truB-2
tRNA pseudouridine synthase subunit A (truB); It may also have a function in cell cycle, it is a cbf5 homolog; Translation, Aminoacyl tRNA synthetases.
   
 0.993
eiF2A
Translation initiation factor aif-2 (eiF2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
  
  
 0.990
priS
DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...]
     
 0.949
rpl44E
LSU ribosomal protein L44E (rpl44E); Binds to the 23S rRNA.
  
    0.915
rpoL
DNA-directed RNA polymerase, subunit L (rpoL); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
    0.891
SSO0939
Pre mRNA splicing protein; Regulation, RNA modification.
   
  
 0.868
rps27E
SSU ribosomal protein S27E (rps27E); Translation, Ribosomal Proteins.
  
    0.864
SSO1049
Hypothetical protein.
       0.852
Your Current Organism:
Saccharolobus solfataricus
NCBI taxonomy Id: 273057
Other names: S. solfataricus P2, Saccharolobus solfataricus P2, Sulfolobus solfataricus P2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.