node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aif2/5b | cysS | STK_02790 | STK_22440 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | 0.734 |
aif2/5b | rpl11p | STK_02790 | STK_13680 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.998 |
aif2/5b | rpl15p | STK_02790 | STK_04120 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 50S ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
aif2/5b | rpl5p | STK_02790 | STK_04200 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.999 |
aif2/5b | rps12p | STK_02790 | STK_02720 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. | 0.999 |
aif2/5b | rps14p | STK_02790 | STK_04195 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 30S ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. | 0.999 |
aif2/5b | rps15p | STK_02790 | STK_03840 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 30S ribosomal protein S15P/S13e. | 0.999 |
aif2/5b | thrS1 | STK_02790 | STK_09660 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.951 |
aif2/5b | thrS2 | STK_02790 | STK_21870 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | Misacylated tRNA(Thr) hydrolase; N-term changed (+354); protein synonym:ThrRS-2; protein synonym:threonyl-tRNA synthetase editing domain. | 0.910 |
aif2/5b | valS | STK_02790 | STK_12240 | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.821 |
cysS | aif2/5b | STK_22440 | STK_02790 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.734 |
cysS | rpl11p | STK_22440 | STK_13680 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | 0.649 |
cysS | rpl5p | STK_22440 | STK_04200 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | 50S ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. | 0.492 |
cysS | rps12p | STK_22440 | STK_02720 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | 30S ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. | 0.420 |
cysS | rps15p | STK_22440 | STK_03840 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | 30S ribosomal protein S15P/S13e. | 0.539 |
cysS | thrS1 | STK_22440 | STK_09660 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also activates L-serine and transfers it to tRNA(Thr) but cannot deacylate incorrectly charged amino acid; unlike most archaea the editing function is found in a freestanding protein. | 0.916 |
cysS | thrS2 | STK_22440 | STK_21870 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | Misacylated tRNA(Thr) hydrolase; N-term changed (+354); protein synonym:ThrRS-2; protein synonym:threonyl-tRNA synthetase editing domain. | 0.434 |
cysS | valS | STK_22440 | STK_12240 | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. | 0.930 |
rpl11p | aif2/5b | STK_13680 | STK_02790 | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | Translation initiation factor aIF2/5B; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.998 |
rpl11p | cysS | STK_13680 | STK_22440 | 50S ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. | cysteinyl-tRNA synthetase; N-term changed (-9); protein synonym:cysteine--tRNA ligase. | 0.649 |