STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aspCAspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (399 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.974
lysC
Protein synonym:aspartokinase; Belongs to the aspartokinase family.
 0.963
ST0294
Prephenate dehydrogenase.
  
 
 0.951
argG
Argininosuccinate synthase; Protein synonym:citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.951
tyrA
Putative chorismate mutase/prephenate dehydrogenase.
    
 0.949
hisC
Histidinol-phosphate aminotransferase; N-term changed (+213).
 
 
0.944
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.940
pyrB
Aspartate carbamoyltransferase.
 
  
 0.940
gdh-2
NADP-dependent glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.928
ST1827
Putative L-asparaginase.
   
 0.923
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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