node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aspC | glyA | STK_12250 | STK_13540 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.583 |
aspC | tdcB | STK_12250 | STK_02950 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Threonine dehydratase. | 0.588 |
aspC | trpA | STK_12250 | STK_12320 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.877 |
aspC | trpB | STK_12250 | STK_12330 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.821 |
aspC | trpC | STK_12250 | STK_12260 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.883 |
aspC | trpD | STK_12250 | STK_12310 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.884 |
aspC | trpE | STK_12250 | STK_12290 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.903 |
aspC | trpF | STK_12250 | STK_12300 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | N- (5'-phosphoribosyl) anthranilate isomerase; N-term changed (+165); Belongs to the TrpF family. | 0.882 |
aspC | trpG | STK_12250 | STK_12280 | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | Anthranilate synthase component II. | 0.883 |
glyA | aspC | STK_13540 | STK_12250 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.583 |
glyA | tdcB | STK_13540 | STK_02950 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase. | 0.952 |
glyA | trpA | STK_13540 | STK_12320 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.946 |
glyA | trpB | STK_13540 | STK_12330 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.908 |
glyA | trpB-2 | STK_13540 | STK_15670 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.908 |
glyA | trpD | STK_13540 | STK_12310 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.458 |
glyA | trpE | STK_13540 | STK_12290 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.719 |
glyA | trpG | STK_13540 | STK_12280 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase component II. | 0.486 |
tdcB | aspC | STK_02950 | STK_12250 | Threonine dehydratase. | Aspartate aminotransferase; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. | 0.588 |
tdcB | glyA | STK_02950 | STK_13540 | Threonine dehydratase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.952 |
tdcB | trpA | STK_02950 | STK_12320 | Threonine dehydratase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.938 |