node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
carA | carB | STK_15030 | STK_15040 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain. | 0.999 |
carA | pyrB | STK_15030 | STK_14800 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase. | 0.999 |
carA | pyrC | STK_15030 | STK_14780 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.986 |
carA | pyrD | STK_15030 | STK_14770 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.914 |
carA | pyrE | STK_15030 | STK_14810 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.996 |
carA | pyrF | STK_15030 | STK_14820 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.996 |
carA | pyrH | STK_15030 | STK_13000 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.456 |
carA | pyrI | STK_15030 | STK_14790 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.983 |
carA | pyrK | STK_15030 | STK_14785 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase electron transfer subunit; N-term changed (+351). | 0.992 |
carA | upp | STK_15030 | STK_02810 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.740 |
carB | carA | STK_15040 | STK_15030 | Carbamoyl-phosphate synthase large chain. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |
carB | pyrB | STK_15040 | STK_14800 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase. | 0.999 |
carB | pyrC | STK_15040 | STK_14780 | Carbamoyl-phosphate synthase large chain. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.988 |
carB | pyrD | STK_15040 | STK_14770 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.929 |
carB | pyrE | STK_15040 | STK_14810 | Carbamoyl-phosphate synthase large chain. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.998 |
carB | pyrF | STK_15040 | STK_14820 | Carbamoyl-phosphate synthase large chain. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.997 |
carB | pyrH | STK_15040 | STK_13000 | Carbamoyl-phosphate synthase large chain. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.628 |
carB | pyrI | STK_15040 | STK_14790 | Carbamoyl-phosphate synthase large chain. | Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.984 |
carB | pyrK | STK_15040 | STK_14785 | Carbamoyl-phosphate synthase large chain. | Dihydroorotate dehydrogenase electron transfer subunit; N-term changed (+351). | 0.997 |
carB | upp | STK_15040 | STK_02810 | Carbamoyl-phosphate synthase large chain. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.666 |