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lysW protein (Sulfolobus tokodaii) - STRING interaction network
"lysW" - Alpha-aminoadipate/glutamate carrier protein LysW in Sulfolobus tokodaii
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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lysWAlpha-aminoadipate/glutamate carrier protein LysW; Carrier protein that bears the covalently bound substrates for arginine and lysine biosynthesis; bound L-glutamate is sequentially converted to L-ornithine, while bound alpha- aminoadipate (AAA) is sequentially converted to L-lysine (56 aa)    
Predicted Functional Partners:
lysX
Alpha-aminoadipate--LysW ligase LysX; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of alpha-aminoadipate (AAA) and the gamma- carboxyl group of the C-terminal glutamate residue in LysW (285 aa)
     
 
  0.974
argB/lysZ
[LysW]-aminoadipate/[LysW]-glutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily (261 aa)
         
  0.967
argC/lysY
[LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily (349 aa)
         
  0.959
lysK
[LysW]-lysine/[LysW]-ornithine hydrolase; Catalyzes the release of L-lysine from [LysW]-gamma-L- lysine and the release of L-ornithine from [LysW]-L-ornithine (346 aa)
         
  0.947
argD/lysJ
[LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily (387 aa)
         
  0.942
uppS
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific); Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids (262 aa)
              0.935
argX
Glutamate--LysW ligase ArgX; Catalyzes the ATP-dependent formation of a covalent bond between the amino group of glutamate and the gamma-carboxyl group of the C-terminal glutamate residue in LysW; Belongs to the RimK family. LysX subfamily (282 aa)
     
 
  0.929
rps8e
annotation not available (128 aa)
              0.915
lysM
HTH-type transcriptional regulator LysM; In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway (140 aa)
         
  0.901
srp19
annotation not available (91 aa)
              0.859
Your Current Organism:
Sulfolobus tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii, Sulfolobus tokodaii str. 7, Sulfolobus tokodaii strain 7
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