Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ST0348Putative formate dehydrogenase. (654 aa)    
Predicted Functional Partners:
ST1789
Hypothetical protein.
 
 0.925
ST0092
Ferredoxin reductase; N-term changed (+87).
   
 0.919
ST0081
Putative formate dehydrogenase.
 
  
 
0.910
ST1839
Hypothetical protein.
 
 
 0.891
moaD/moaE
Molybdopterin converting factor; Protein synonym:molybdopterin synthase MoaE/MoaD.
 
   
 0.849
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
    
 0.822
fumC
Fumarate hydratase; N-term changed (-3); protein synonym:fumarase C.
    
 0.808
ST0114
Malate dehydrogenase; Protein synonym:NADP(+)-dependent malic enzyme.
    
 0.802
ST0278
Malate dehydrogenase; N-term changed (-51); protein synonym:NADP(+)-dependent malic enzyme.
    
 0.802
pckG
Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
     
 0.800
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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