STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
shdBSuccinate dehydrogenase iron-sulfur protein subunit; Protein synonym:succinate--caldariellaquinone oxidoreductase. (320 aa)    
Predicted Functional Partners:
sdhA
Succinate dehydrogenase flavoprotein subunit; Protein synonym:succinate--caldariellaquinone oxidoreductase.
 
 0.999
sucD
succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.997
nuoI
Putative NADH-quinone oxidoreductase subunit I; N-term changed (-6).
  
 
 0.997
sucC
succinyl-CoA synthetase beta subunit; N-term changed (+195); N-terminus of this ORF was identified by Edman sequencing; protein synonym:succinate---CoA ligase.
 
 0.996
sdhC
Succinate dehydrogenase subunit SdhC; Protein synonym:CCG-domain-containing subunit SdhE; protein synonym:succinate--caldariellaquinone oxidoreductase.
 
 
 0.993
fumC
Fumarate hydratase; N-term changed (-3); protein synonym:fumarase C.
 
 0.992
nuoD
Putative NADH-quinone oxidoreductase subunit D; N-term changed (+36); Belongs to the complex I 49 kDa subunit family.
  
 
 0.989
sdhD
Succinate dehydrogenase subunit SdhD; Protein synonym:succinate--caldariellaquinone oxidoreductase.
    
  0.984
nuoC
Putative NADH-quinone oxidoreductase subunit C.
  
 
 0.961
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 
 0.933
Your Current Organism:
Sulfurisphaera tokodaii
NCBI taxonomy Id: 273063
Other names: S. tokodaii str. 7, Sulfolobus sp. (strain 7), Sulfolobus sp. 7, Sulfolobus tokodaii str. 7, Sulfurisphaera tokodaii str. 7, Sulfurisphaera tokodaii strain 7
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