node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DdlA2 | MurB | TTE2545 | TTE1836 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.979 |
DdlA2 | MurD | TTE2545 | TTE1647 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.706 |
DdlA2 | MurG | TTE2545 | TTE1645 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.920 |
DdlA2 | MurI | TTE2545 | TTE0209 | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.623 |
FtsK | LysA | TTE1378 | TTE0210 | DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.483 |
FtsK | MurG | TTE1378 | TTE1645 | DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.518 |
FtsK | MurI | TTE1378 | TTE0209 | DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.660 |
LysA | FtsK | TTE0210 | TTE1378 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | 0.483 |
LysA | MurI | TTE0210 | TTE0209 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.862 |
MurB | DdlA2 | TTE1836 | TTE2545 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.979 |
MurB | MurD | TTE1836 | TTE1647 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.971 |
MurB | MurG | TTE1836 | TTE1645 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.954 |
MurB | MurI | TTE1836 | TTE0209 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.689 |
MurB | MurI2 | TTE1836 | TTE0595 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.417 |
MurB | MurI3 | TTE1836 | TTE1225 | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.417 |
MurD | DdlA2 | TTE1647 | TTE2545 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | D-alanine-D-alanine ligase and related ATP-grasp enzymes; Cell wall formation. | 0.706 |
MurD | MurB | TTE1647 | TTE1836 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.971 |
MurD | MurG | TTE1647 | TTE1645 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.998 |
MurD | MurI | TTE1647 | TTE0209 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.967 |
MurD | MurI2 | TTE1647 | TTE0595 | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.965 |