STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CspRPredicted rRNA methylase (SpoU class); Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (156 aa)    
Predicted Functional Partners:
DinP
Nucleotidyltransferase/DNA polymerase involved in DNA repair; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
       0.784
NorM
Na+-driven multidrug efflux pump; Best Blastp hit = gi|7462346|pir||H72331 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981345|gb|AAD35897.1|AE001748_13 (AE001748) conserved hypothetical protein [Thermotoga maritima], score 206, E-value 5.00E-52.
  
    0.783
TpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
      0.723
PhnL
ABC-type transport systems, involved in lipoprotein release, ATPase components; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
       0.523
AcrA
Membrane-fusion protein; Best Blastp hit = gi|12721480|gb|AAK03218.1| (AE006154) unknown [Pasteurella multocida], score 78.6, E-value 2.00E-13.
       0.512
TTE0258
ABC-type transport systems, involved in lipoprotein release, permease components; Best Blastp hit = gi|7469821|pir||S76946 hypothetical protein - Synechocystis sp. (strain PCC 6803) gi|1653948|dbj|BAA18858.1| (D90917) hypothetical protein [Synechocystis sp.], score 185, E-value 8.00E-46.
       0.512
SplB
DNA repair photolyase; Best Blastp hit = gi|586030|sp|P37956|SPL_BACSU SPORE PHOTOPRODUCT LYASE gi|421532|pir||C47084 spore photoproduct lyase splB - Bacillus subtilis gi|289270|gb|AAA22416.1| (L08809) spore photoproduct lyase [Bacillus subtilis] gi|2633764|emb|CAB13266.1| (Z99111) spore photoproduct lyase [Bacillus subtilis], score 70.9, E-value 2.00E-11.
 
     0.443
DegV
Conserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
 
    0.438
Sun2
tRNA and rRNA cytosine-C5-methylases; Best Blastp hit = gi|13622373|gb|AAK34101.1| (AE006564) putative nucleolar protein [Streptococcus pyogenes], score 280, E-value 3.00E-74.
     
 0.418
OadB
Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
       0.415
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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