Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Fur2Fe2+/Zn2+ uptake regulation proteins; Best Blastp hit = gi|10174012|dbj|BAB05115.1| (AP001511) transcriptional regulator (Fur family) [Bacillus halodurans], score 109, E-value 1.00E-23; Belongs to the Fur family. (138 aa)    
Predicted Functional Partners:
ZnuA
ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding (lipo)protein (surface adhesin A); Best Blastp hit = gi|12725170|gb|AAK06213.1|AE006439_10 (AE006439) zinc ABC transporter substrate binding protein [Lactococcus lactis subsp. lactis], score 197, E-value 2.00E-49; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.859
ZnuC
ABC-type Mn/Zn transport systems, ATPase component; Best Blastp hit = gi|10174010|dbj|BAB05113.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus halodurans], score 213, E-value 2.00E-54.
  
  
 0.579
ZnuB
ABC-type Mn2+/Zn2+ transport systems, permease components; Best Blastp hit = gi|10174011|dbj|BAB05114.1| (AP001511) ABC transporter (permease) [Bacillus halodurans], score 173, E-value 2.00E-42.
  
  
 0.564
TTE0367
MoxR-like ATPases; Best Blastp hit = gi|10173218|dbj|BAB04323.1| (AP001509) methanol dehydrogenase regulatory protein [Bacillus halodurans], score 358, E-value 7.00E-98.
  
    0.541
RpoA
DNA-directed RNA polymerase alpha subunit/40 kD subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.536
TTE0368
Conserved hypothetical protein; Best Blastp hit = gi|1496004|gb|AAB06263.1| (L39876) ORF1; PepX [Caldicellulosiruptor saccharolyticus], score 148, E-value 1.00E-34.
       0.533
TTE0369
Hypothetical protein.
       0.533
TTE1857
Hypothetical protein.
  
  
 0.434
AhpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.419
AhpC2
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.419
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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