Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MalF2ABC-type sugar transport systems, permease components; Best Blastp hit = gi|11277399|pir||T46751 inner membrane protein malF [validated] - Thermococcus litoralis gi|2828821|gb|AAC38137.1| (AF012836) inner membrane protein MalF [Thermococcus litoralis], score 182, E-value 5.00E-45. (286 aa)    
Predicted Functional Partners:
MalG2
Sugar permeases; Best Blastp hit = gi|13814186|gb|AAK41272.1| (AE006719) Sugar ABC transporter [Sulfolobus solfataricus], score 177, E-value 1.00E-43.
 0.998
UgpB2
Sugar-binding periplasmic proteins/domains; Best Blastp hit = gi|13814184|gb|AAK41270.1| (AE006719) ABC Transporter [Sulfolobus solfataricus], score 170, E-value 4.00E-41.
 
 0.997
MalK
ABC-type sugar/spermidine/putrescine/iron/thiamine transport systems, ATPase component; Best Blastp hit = gi|7959056|dbj|BAA95937.1| (AB035092) Orf5 [Clostridium perfringens], score 499, E-value 1.00E-140; Belongs to the ABC transporter superfamily.
 
 
 0.988
MalF
Best Blastp hit = gi|10176313|dbj|BAB07408.1| (AP001519) sugar transport system (permease) [Bacillus halodurans], score 239, E-value 5.00E-62.
 
  
0.963
MalE
Maltose-binding periplasmic proteins/domains; Best Blastp hit = gi|6686562|emb|CAB65651.1| (AJ252161) maltose binding protein [Alicyclobacillus acidocaldarius], score 312, E-value 5.00E-84.
 
 0.931
MalG6
Sugar permeases; Best Blastp hit = gi|7481610|pir||T35672 probable transmembrane transport protein - Streptomyces coelicolor gi|2661679|emb|CAA15784.1| (AL009199) probable transmembrane transport protein [Streptomyces coelicolor A3(2)], score 187, E-value 2.00E-46.
 
 0.908
MalG3
Sugar permeases; Best Blastp hit = gi|6686564|emb|CAB65653.1| (AJ252161) putative maltose transport membrane protein [Alicyclobacillus acidocaldarius], score 295, E-value 4.00E-79.
 
0.907
MalG5
Sugar permeases; Best Blastp hit = gi|10176306|dbj|BAB07401.1| (AP001519) sugar ABC transporter (permease) [Bacillus halodurans], score 228, E-value 6.00E-59.
 
 0.905
UgpB
Sugar-binding periplasmic proteins/domains; Best Blastp hit = gi|10176314|dbj|BAB07409.1| (AP001519) sugar transport system (sugar-binding protein) [Bacillus halodurans], score 286, E-value 3.00E-76.
 
 0.891
MalG
Sugar permeases; Best Blastp hit = gi|10176312|dbj|BAB07407.1| (AP001519) sugar transport system (permease) [Bacillus halodurans], score 289, E-value 3.00E-77.
 
0.874
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
Server load: low (12%) [HD]