Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ath1.2Trehalose and maltose hydrolases (possible phosphorylases); Best Blastp hit = gi|6752337|emb|CAB69693.1| (AL137165) putative glycosyl transferase. [Streptomyces coelicolor A3(2)], score 525, E-value 1.00E-148. (781 aa)    
Predicted Functional Partners:
TTE0802
Predicted phosphatase/phosphohexomutase; Best Blastp hit = gi|3024396|sp|O06995|PGMB_BACSU PUTATIVE BETA-PHOSPHOGLUCOMUTASE (BETA-PGM) gi|7429460|pir||E70034 beta-phosphoglucomutase homolog yvdM - Bacillus subtilis gi|1945672|emb|CAB08042.1| (Z94043) hypothetical protein [Bacillus subtilis] gi|2635968|emb|CAB15460.1| (Z99121) similar to beta-phosphoglucomutase [Bacillus subtilis], score 207, E-value 9.00E-53.
 
 0.999
TTE1983
Predicted phosphatase/phosphohexomutase; Best Blastp hit = gi|7445120|pir||H72277 hypothetical protein TM1254 - Thermotoga maritima (strain MSB8) gi|4981809|gb|AAD36329.1|AE001780_13 '(AE001780) beta-phosphoglucomutase, putative [Thermotoga maritima]', score 124, E-value 1.00E-27.
  
 0.847
UgpB2
Sugar-binding periplasmic proteins/domains; Best Blastp hit = gi|13814184|gb|AAK41270.1| (AE006719) ABC Transporter [Sulfolobus solfataricus], score 170, E-value 4.00E-41.
 
   
 0.696
Pgk
3-phosphoglycerate kinase; Best Blastp hit = gi|129919|sp|P18912|PGK_BACST PHOSPHOGLYCERATE KINASE gi|80216|pir||JQ1399 phosphoglycerate kinase (EC 2.7.2.3) - Bacillus stearothermophilus gi|576239|pdb|1PHP| 3-Phosphoglycerate Kinase (Pgk) (E.C.2.7.2.3) gi|48855|emb|CAA41093.1| (X58059) 3-phosphoglycerate kinase [Bacillus stearothermophilus], score 509, E-value 1.00E-143.
   
  
 0.640
MalF2
ABC-type sugar transport systems, permease components; Best Blastp hit = gi|11277399|pir||T46751 inner membrane protein malF [validated] - Thermococcus litoralis gi|2828821|gb|AAC38137.1| (AF012836) inner membrane protein MalF [Thermococcus litoralis], score 182, E-value 5.00E-45.
  
  
 0.638
Pgi
Glucose-6-phosphate isomerase; Best Blastp hit = gi|120717|sp|P13375|G6PA_BACST GLUCOSE-6-PHOSPHATE ISOMERASE A (GPI A) (PHOSPHOGLUCOSE ISOMERASE A) (PGI-A) gi|68452|pir||NUBSSA glucose-6-phosphate isomerase (EC 5.3.1.9) A [validated] - Bacillus stearothermophilus gi|40046|emb|CAA34634.1| (X16639) phosphoglucose isomerase A (AA 1-449) [Bacillus stearothermophilus], score 617, E-value 1.00E-176.
     
 0.626
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
   
  
 0.625
SppA
Periplasmic serine proteases (ClpP class); Best Blastp hit = gi|7451825|pir||E69990 proteinase IV homolog yteI - Bacillus subtilis gi|2293234|gb|AAC00312.1| (AF008220) putative protease [Bacillus subtilis] gi|2635437|emb|CAB14931.1| (Z99119) similar to protease IV [Bacillus subtilis], score 202, E-value 3.00E-51.
      
 0.618
GalE
UDP-glucose 4-epimerase; Best Blastp hit = gi|11386836|sp|Q9KDV3|GALE_BACHD UDP-GLUCOSE 4-EPIMERASE (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) gi|10173723|dbj|BAB04827.1| (AP001510) UDP-glucose 4-epimerase [Bacillus halodurans], score 418, E-value 1.00E-116; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
      
 0.618
MalG2
Sugar permeases; Best Blastp hit = gi|13814186|gb|AAK41272.1| (AE006719) Sugar ABC transporter [Sulfolobus solfataricus], score 177, E-value 1.00E-43.
  
  
 0.614
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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