STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTE0919Predicted HD superfamily hydrolase involved in NAD metabolism; Best Blastp hit = gi|10173943|dbj|BAB05046.1| (AP001511) BH1327; unknown conserved protein [Bacillus halodurans], score 149, E-value 3.00E-35. (198 aa)    
Predicted Functional Partners:
NadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
  
 0.997
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
    0.965
LytR3
Transcriptional regulator; Best Blastp hit = gi|7430406|pir||S75661 membrane-bound protein lytR - Synechocystis sp. (strain PCC 6803) gi|1653307|dbj|BAA18222.1| (D90912) membrane bound protein LytR [Synechocystis sp.], score 155, E-value 7.00E-37.
 
    0.831
TTE0914
Predicted ribosomal protein; Best Blastp hit = gi|10175632|dbj|BAB06729.1| (AP001517) BH3010; unknown conserved protein in B. subtilis [Bacillus halodurans], score 52.8, E-value 1.00E-06.
 
    0.727
Obg
Predicted GTPase; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
    0.724
PolC
DNA polymerase III alpha subunit, the Gram-positive type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
     0.678
RplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.663
RpmA
Ribosomal protein L27; Best Blastp hit = gi|13701443|dbj|BAB42737.1| (AP003134) 50S ribosomal protei L27 (BL30) [Staphylococcus aureus], score 134, E-value 4.00E-31; Belongs to the bacterial ribosomal protein bL27 family.
       0.663
TTE0912
Hypothetical protein.
  
    0.658
TTE0922
Conserved hypothetical protein; Best Blastp hit = gi|7479980|pir||T36435 hypothetical protein SCF43A.12c - Streptomyces coelicolor gi|5459226|emb|CAB48899.1| (AL096837) hypothetical protein [Streptomyces coelicolor A3(2)], score 107, E-value 1.00E-22.
       0.599
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.