STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NagB6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (253 aa)    
Predicted Functional Partners:
NagA
N-acetylglucosamine-6-phosphate deacetylase; Best Blastp hit = gi|10173034|dbj|BAB04140.1| (AP001508) N-acetylglucosamine-6-phosphate deacetylase [Bacillus halodurans], score 316, E-value 3.00E-85.
 0.999
Pgi
Glucose-6-phosphate isomerase; Best Blastp hit = gi|120717|sp|P13375|G6PA_BACST GLUCOSE-6-PHOSPHATE ISOMERASE A (GPI A) (PHOSPHOGLUCOSE ISOMERASE A) (PGI-A) gi|68452|pir||NUBSSA glucose-6-phosphate isomerase (EC 5.3.1.9) A [validated] - Bacillus stearothermophilus gi|40046|emb|CAA34634.1| (X16639) phosphoglucose isomerase A (AA 1-449) [Bacillus stearothermophilus], score 617, E-value 1.00E-176.
  
 0.943
GlmS
Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.934
ManA
Phosphomannose isomerase; Best Blastp hit = gi|13249157|gb|AAK16707.1| (AF324506) mannose-6-phosphate isomerase [Bacillus subtilis], score 211, E-value 8.00E-54.
     
 0.917
CpsG2
Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.917
PtsG
Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; Best Blastp hit = gi|10173035|dbj|BAB04141.1| '(AP001508) PTS system, N-acetylglucosamine-specific enzyme II, ABC component [Bacillus halodurans]', score 418, E-value 1.00E-116.
  
 0.885
Zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
  
 0.752
NanE
Putative N-acetylmannosamine-6-phosphate epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
   
 0.709
MtlD
Mannitol-1-phosphate/altronate dehydrogenases; Best Blastp hit = gi|8134573|sp|O65992|MTLD_CLOAB MANNITOL-1-PHOSPHATE 5-DEHYDROGENASE gi|3025457|gb|AAC12851.1| (U53868) MtlD [Clostridium acetobutylicum], score 404, E-value 1.00E-111.
    
 0.704
FruA
Best Blastp hit = gi|131491|sp|P23387|PTFB_RHOCA 'PTS SYSTEM, FRUCTOSE-SPECIFIC IIBC COMPONENT (EIIBC-FRU) (FRUCTOSE-PERMEASE IIBC COMPONENT) (PHOSPHOTRANSFERASE ENZYME II, BC COMPONENT) (EII-FRU)' gi|97494|pir||B37852 'phosphotransferase system enzyme II (EC 2.7.1.69), fructose-specific - Rhodobacter capsulatus' gi|46021|emb|CAA37303.1| (X53150) fructose enzyme II [Rhodobacter capsulatus], score 537, E-value 1.00E-152.
      
 0.611
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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