Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PaaKCoenzyme F390 synthetase; Best Blastp hit = gi|10172807|dbj|BAB03914.1| (AP001507) phenylacetyl-CoA ligase in the phenylacetic acid catabolic pathway [Bacillus halodurans], score 82, E-value 1.00E-14. (445 aa)    
Predicted Functional Partners:
PorA5
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
 
    0.751
PorG3
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit; Best Blastp hit = gi|6685561|sp|O58496|IORB_PYRHO INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORB (IOR) (INDOLEPYRUVATE FERREDOXIN OXIDOREDUCTASE BETA SUBUNIT) gi|7430384|pir||E71124 probable indolepyruvate ferredoxin oxidoreductase beta subunit - Pyrococcus horikoshii gi|3257172|dbj|BAA29855.1| (AP000003) 202aa long hypothetical indolepyruvate ferredoxin oxidoreductase beta subunit [Pyrococcus horikoshii], score 140, E-value 1.00E-32.
 
    0.699
TrxA
Thiol-disulfide isomerase and thioredoxins; Best Blastp hit = gi|7451068|pir||E69891 cytochrome c biogenesis protein CycX homolog homolog yneN [similarity] - Bacillus subtilis gi|2634185|emb|CAB13685.1| (Z99113) similar to thiol:disulfide interchange protein [Bacillus subtilis], score 101, E-value 8.00E-21.
     
 0.585
CcdA
Cytochrome c biogenesis protein; Best Blastp hit = gi|10173810|dbj|BAB04913.1| (AP001511) required for a late step of cytochrome c synthesis [Bacillus halodurans], score 176, E-value 2.00E-43.
       0.570
NagB
6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
       0.554
PorA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
  
 0.514
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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