node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ComFC | TyrA | TTE0490 | TTE1014 | Predicted amidophosphoribosyltransferases; Best Blastp hit = gi|13472985|ref|NP_104552.1| 'hypothetical protein, similar to competence protein F [Mesorhizobium loti]' gi|14023733|dbj|BAB50338.1| (AP003002) hypothetical protein [Mesorhizobium loti], score 131, E-value 7.00E-30. | Prephenate dehydrogenase; Best Blastp hit = gi|10174283|dbj|BAB05385.1| (AP001512) prephenate dehydrogenase [Bacillus halodurans], score 161, E-value 8.00E-39. | 0.654 |
ComFC | XerC2 | TTE0490 | TTE1363 | Predicted amidophosphoribosyltransferases; Best Blastp hit = gi|13472985|ref|NP_104552.1| 'hypothetical protein, similar to competence protein F [Mesorhizobium loti]' gi|14023733|dbj|BAB50338.1| (AP003002) hypothetical protein [Mesorhizobium loti], score 131, E-value 7.00E-30. | Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. | 0.491 |
FtsK | TopA | TTE1378 | TTE1449 | DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.713 |
FtsK | XerC2 | TTE1378 | TTE1363 | DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family. | Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. | 0.495 |
Hfq | MutL | TTE1360 | TTE1358 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.836 |
Hfq | MutS2 | TTE1360 | TTE1357 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.718 |
Hfq | ProC | TTE1360 | TTE1361 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.578 |
Hfq | RnhA | TTE1360 | TTE1362 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.648 |
Hfq | XerC2 | TTE1360 | TTE1363 | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. | 0.539 |
HslV | TopA | TTE1448 | TTE1449 | Proteasome protease subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.775 |
HslV | XerC2 | TTE1448 | TTE1363 | Proteasome protease subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. | 0.562 |
MutL | Hfq | TTE1358 | TTE1360 | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.836 |
MutL | MutS2 | TTE1358 | TTE1357 | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.996 |
MutL | ProC | TTE1358 | TTE1361 | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.579 |
MutL | RnhA | TTE1358 | TTE1362 | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.595 |
MutL | TopA | TTE1358 | TTE1449 | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...] | 0.481 |
MutL | XerC2 | TTE1358 | TTE1363 | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Integrase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Belongs to the 'phage' integrase family. | 0.513 |
MutS2 | Hfq | TTE1357 | TTE1360 | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | Uncharacterized ACR, host factor I protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.718 |
MutS2 | MutL | TTE1357 | TTE1358 | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | DNA mismatch repair enzyme (predicted ATPase); This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.996 |
MutS2 | ProC | TTE1357 | TTE1361 | MutS-like ATPases involved in mismatch repair, family 2; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.510 |