STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PqqLPredicted Zn-dependent peptidase; Best Blastp hit = gi|10175025|dbj|BAB06124.1| (AP001515) processing protease [Bacillus halodurans], score 320, E-value 3.00E-86; Belongs to the peptidase M16 family. (420 aa)    
Predicted Functional Partners:
NuoF
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Best Blastp hit = gi|7431975|pir||D72430 'NADP-reducing hydrogenase, subunit C - Thermotoga maritima (strain MSB8)' gi|4980493|gb|AAD35104.1|AE001689_10 '(AE001689) NADP-reducing hydrogenase, subunit C [Thermotoga maritima]', score 757, E-value 0.
  
 
 0.990
NuoE
NADH:ubiquinone oxidoreductase 24 kD subunit; Best Blastp hit = gi|2126446|pir||A57150 NADP-reducing hydrogenase (EC 1.-.-.-) chain A - Desulfovibrio fructosovorans gi|466363|gb|AAA87054.1| (U07229) potential NAD-reducing hydrogenase subunit [Desulfovibrio fructosovorans], score 157, E-value 1.00E-37.
   
 
 0.862
TTE0126
echD; Best Blastp hit = gi|3005970|emb|CAA76120.1| (Y16191) echD [Methanosarcina barkeri], score 78.2, E-value 4.00E-14.
   
 
 0.851
TTE1383
Conserved hypothetical protein; Best Blastp hit = gi|10175024|dbj|BAB06123.1| (AP001515) BH2404; unknown conserved protein [Bacillus halodurans], score 62, E-value 2.00E-09.
  
    0.816
Dut
dUTPase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.808
AcpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 
 0.804
DnaJ
Molecular chaperones (contain C-terminal Zn finger domain); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-de [...]
   
 
 0.733
Pnp
Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.705
Cda1.2
Predicted xylanase/chitin deacetylase; Best Blastp hit = gi|7474808|pir||H69882 deacetylase homolog ylxY - Bacillus subtilis gi|2634042|emb|CAB13543.1| (Z99112) alternate gene name: ymxI; similar to deacetylase [Bacillus subtilis], score 190, E-value 1.00E-47.
  
    0.698
AtpH
F0F1-type ATP synthase delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family.
   
 
 0.679
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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