STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (122 aa)    
Predicted Functional Partners:
TruB
Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
 
  
 0.991
InfB
Translation initiation factor 2 (GTPase); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
 
  
 0.991
TTE1391
Exopolyphosphatase-related proteins; Best Blastp hit = gi|7445472|pir||F70440 conserved hypothetical protein aq_1630 - Aquifex aeolicus gi|2983973|gb|AAC07520.1| (AE000748) hypothetical protein [Aquifex aeolicus], score 186, E-value 3.00E-46.
 
  
 0.980
rimP
Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
 
 0.973
RpsO
Ribosomal protein S15P/S13E; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
  
 
 0.964
NusA
Transcription terminator; Participates in both transcription termination and antitermination.
  
  
 0.916
RpsG
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.915
RpsL
Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.911
TTE1395
Predicted nucleic-acid-binding protein implicated in transcription termination; Best Blastp hit = gi|10175035|dbj|BAB06134.1| (AP001515) BH2415; unknown conserved protein [Bacillus halodurans], score 80.5, E-value 4.00E-15.
  
    0.906
RibF
FAD synthase; Best Blastp hit = gi|7444639|pir||D70313 riboflavin kinase - Aquifex aeolicus gi|2982868|gb|AAC06488.1| (AE000675) riboflavin kinase [Aquifex aeolicus], score 193, E-value 3.00E-48; Belongs to the ribF family.
 
   
 0.895
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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