STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MesJ2Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Best Blastp hit = gi|11346616|pir||F81428 hypothetical protein Cj0118 [imported] - Campylobacter jejuni (strain NCTC 11168) gi|6967612|emb|CAB72602.1| (AL139074) hypothetical protein Cj0118 [Campylobacter jejuni], score 142, E-value 5.00E-33; Belongs to the TtcA family. (235 aa)    
Predicted Functional Partners:
CsdB
Selenocysteine lyase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
 
      0.855
TTE0769
ATP-utilizing enzymes of the PP-loop superfamily; Best Blastp hit = gi|7451266|pir||C72312 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981504|gb|AAD36045.1|AE001759_9 (AE001759) conserved hypothetical protein [Thermotoga maritima], score 209, E-value 4.00E-53.
 
    0.837
TTE2469
Hypothetical protein.
  
 
 0.630
TTE1526
Predicted SAM-dependent methyltransferases; Best Blastp hit = gi|7445421|pir||C72220 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4982274|gb|AAD36764.1|AE001810_3 (AE001810) conserved hypothetical protein [Thermotoga maritima], score 336, E-value 4.00E-91.
       0.566
MetG
Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.469
GuaA
GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.444
TTE1528
Putative peptidoglycan-binding domain-containing protein; Best Blastp hit = gi|5701723|dbj|BAA83081.1| (AB023893) penicillin-resistant DD-carboxypeptidase [Myxococcus xanthus], score 66.6, E-value 5.00E-11.
       0.437
Pth
Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.432
Mfd
Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
  
  
 0.419
Gcd14
Predicted SAM-dependent methyltransferase involved in tRNA-Met maturation; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
 
  
 0.409
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.