STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SsnACytosine deaminase and related metal-dependent hydrolases; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (433 aa)    
Predicted Functional Partners:
Pnp2
Purine nucleoside phosphorylase; Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage.
 
 0.993
SpeE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
   
  0.909
SpeE2
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
   
  0.909
Gcn3
Translation initiation factor eIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
  
 0.828
HflC
Membrane protease subunits, stomatin/prohibitin homologs; Best Blastp hit = gi|11499015|ref|NP_070249.1| membrane protein [Archaeoglobus fulgidus] gi|6647985|sp|O28852|YE20_ARCFU HYPOTHETICAL PROTEIN AF1420 gi|7447605|pir||C69427 membrane protein homolog - Archaeoglobus fulgidus gi|2649154|gb|AAB89829.1| (AE001006) membrane protein [Archaeoglobus fulgidus], score 251, E-value 5.00E-66.
 
    0.763
AraD
Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; Best Blastp hit = gi|9955359|pdb|1DZX|P 'Chain P, L-Fuculose-1-Phosphate Aldolase From Escherichia Coli Mutant R212a' gi|9955360|pdb|1DZY|P 'Chain P, L-Fuculose-1-Phosphate Aldolase From Escherichia Coli Mutant E214a', score 139, E-value 2.00E-32.
     
 0.762
IleS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
     
 0.673
CbiQ2
ABC-type cobalt transport system, permease component CbiQ and related transporters; Best Blastp hit = gi|7518348|pir||F75200 hypothetical protein PAB2261 - Pyrococcus abyssi (strain Orsay) gi|5457562|emb|CAB49053.1| (AJ248283) hypothetical protein [Pyrococcus abyssi], score 110, E-value 2.00E-23.
 
     0.658
Tdh2
Threonine dehydrogenase and related Zn-dependent dehydrogenases; Best Blastp hit = gi|7430976|pir||E72597 probable alcohol dehydrogenase APE1245 - Aeropyrum pernix (strain K1) gi|5104921|dbj|BAA80235.1| (AP000061) 332aa long hypothetical alcohol dehydrogenase [Aeropyrum pernix], score 140, E-value 2.00E-32.
  
   0.651
CbiO2
ABC-type cobalt transport system, ATPase component; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
     
 0.619
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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