STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTE1642Conserved hypothetical protein; Best Blastp hit = gi|1075848|pir||C43727 conserved hypothetical protein ylxW - Bacillus subtilis gi|1129091|gb|AAA83971.1| (M31827) ORF4; putative [Bacillus subtilis] gi|2633896|emb|CAB13398.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis], score 126, E-value 2.00E-28. (242 aa)    
Predicted Functional Partners:
TTE1641
Small basic protein; Best Blastp hit = gi|10175180|dbj|BAB06279.1| (AP001515) small basic protein [Bacillus halodurans], score 100, E-value 5.00E-21.
 
  
 0.979
FtsQ
Cell division septal protein; Essential cell division protein.
  
    0.879
FtsZ
Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.860
FtsA2
Predicted ATPases of the HSP70 class involved in cell division; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
       0.844
MurA2
UDP-N-acetylglucosamine enolpyruvyl transferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.645
FtsW2
Bacterial cell division membrane protein; Best Blastp hit = gi|10175186|dbj|BAB06285.1| (AP001515) stage V sporulation protein E (required for spore cortex synthesis) [Bacillus halodurans], score 291, E-value 1.00E-77; Belongs to the SEDS family.
       0.634
MurD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
       0.615
MurG
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
    0.603
TTE0112
Conserved hypothetical protein; Best Blastp hit = gi|586876|sp|P37546|YABE_BACSU HYPOTHETICAL 47.7 KD PROTEIN IN METS-KSGA INTERGENIC REGION gi|2127034|pir||S66069 conserved hypothetical protein yabE - Bacillus subtilis gi|467429|dbj|BAA05275.1| (D26185) unknown [Bacillus subtilis] gi|2632307|emb|CAB11816.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis], score 179, E-value 4.00E-44.
 
     0.587
Rfe2
Phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
       0.568
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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