STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MurGUDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (364 aa)    
Predicted Functional Partners:
MurD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.998
Rfe2
Phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
 
 0.998
MurC
UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
 0.998
FtsW2
Bacterial cell division membrane protein; Best Blastp hit = gi|10175186|dbj|BAB06285.1| (AP001515) stage V sporulation protein E (required for spore cortex synthesis) [Bacillus halodurans], score 291, E-value 1.00E-77; Belongs to the SEDS family.
  
 0.992
MurE2
UDP-N-acetylmuramyl tripeptide synthase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 
 0.989
FtsQ
Cell division septal protein; Essential cell division protein.
  
  
 0.983
MurF
UDP-N-acetylmuramyl pentapeptide synthase; Best Blastp hit = gi|7464026|pir||C71903 D-alanyl-D-alanine-adding enzyme - Helicobacter pylori (strain J99) gi|4155222|gb|AAD06244.1| (AE001499) D-ALANYL-D-ALANINE-ADDING ENZYME [Helicobacter pylori J99], score 212, E-value 1.00E-53.
 
  
 0.982
FtsZ
Cell division GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
 0.980
MurB
UDP-N-acetylmuramate dehydrogenase; Cell wall formation.
 
  
 0.954
MurE
Best Blastp hit = gi|7522162|pir||T31440 UDP-N-acetylmuramyl tripeptide synthetase homolog murC - Heliobacillus mobilis gi|3820539|gb|AAC84012.1| (AF080002) UDP-N-acetylmuramyl tripeptide synthetase MurC [Heliobacillus mobilis], score 298, E-value 1.00E-79.
  
 0.949
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.