STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LgtProlipoprotein diacylglyceryltransferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (257 aa)    
Predicted Functional Partners:
TrpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
  
    0.849
TrpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
    0.816
LspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
 
   
 0.791
YidC
Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).
 
  
 0.708
TTE1742
Thioredoxin-like proteins and domains; Best Blastp hit = gi|10176042|dbj|BAB07138.1| (AP001518) nitrogen fixation protein (NifU protein) [Bacillus halodurans], score 77.8, E-value 2.00E-14.
       0.644
TTE1743
GAF domain-containing proteins; Best Blastp hit = gi|7462250|pir||E72365 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981032|gb|AAD35604.1|AE001728_5 (AE001728) conserved hypothetical protein [Thermotoga maritima], score 109, E-value 2.00E-23.
       0.608
NuoF
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Best Blastp hit = gi|7431975|pir||D72430 'NADP-reducing hydrogenase, subunit C - Thermotoga maritima (strain MSB8)' gi|4980493|gb|AAD35104.1|AE001689_10 '(AE001689) NADP-reducing hydrogenase, subunit C [Thermotoga maritima]', score 757, E-value 0.
  
  
 0.595
HprK
Serine kinase of the HPr protein, regulates carbohydrate metabolism; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence [...]
  
  
 0.584
TTE0923
NAD/NADP octopine/nopaline dehydrogenas; Best Blastp hit = gi|3287880|sp|Q44297|ODH_ARTSP OPINE DEHYDROGENASE (N-(1-D-CARBOXYETHYL)-L-NORVALINE DEHYDROGENASE) gi|2127401|pir||I39664 probable D-octopine dehydrogenase (EC 1.5.1.11) - Arthrobacter sp gi|4389299|pdb|1BG6| Crystal Structure Of The N-(1-D-Carboxylethyl)-L-Norvaline Dehydrogenase From Arthrobacter Sp. Strain 1c gi|1060848|dbj|BAA08145.1| (D45211) opine dehydrogenase [Arthrobacter sp.], score 269, E-value 5.00E-71.
 
  
 0.575
GpsA
Best Blastp hit = gi|7431307|pir||H69636 glycerol-3-phosphate dehydrogenase (NAD+) (EC 1.1.1.8) gpsA - Bacillus subtilis gi|1146220|gb|AAC83967.1| (L47648) NAD+ dependent glycerol-3-phosphate dehydrogenase [Bacillus subtilis] gi|2634701|emb|CAB14199.1| (Z99115) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus subtilis], score 327, E-value 1.00E-88; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
  
 0.552
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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