STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTE1753Conserved hypothetical protein; Best Blastp hit = gi|12644317|sp|P54472|YQFO_BACSU HYPOTHETICAL 40.9 KDA PROTEIN IN CCCA-SODA INTERGENIC REGION gi|7474697|pir||A69954 conserved hypothetical protein yqfO - Bacillus subtilis gi|2634950|emb|CAB14447.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis], score 306, E-value 4.00E-82; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (376 aa)    
Predicted Functional Partners:
TTE1754
Predicted SAM-dependent methyltransferase; Best Blastp hit = gi|10173995|dbj|BAB05098.1| (AP001511) BH1379; unknown conserved protein [Bacillus halodurans], score 110, E-value 2.00E-23.
 
  
 0.994
RnhA
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
  
 0.770
HisC
Histidinol-phosphate aminotransferase/Tyrosine aminotransferase; Decarboxylates L-threonine-O-3-phosphate to yield (R)-1- amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.727
HisC2
Best Blastp hit = gi|7450424|pir||E70478 histidinol-phosphate aminotransferase - Aquifex aeolicus gi|2984289|gb|AAC07813.1| (AE000771) histidinol-phosphate aminotransferase [Aquifex aeolicus], score 230, E-value 2.00E-59.
  
  
 0.727
RpoD4
DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
     
 0.668
DnaG
DNA primase (bacterial type); RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
     
 0.652
GpmB
Best Blastp hit = gi|7451679|pir||G72260 phosphoglycerate mutase - Thermotoga maritima (strain MSB8) gi|4981935|gb|AAD36444.1|AE001791_6 (AE001791) phosphoglycerate mutase [Thermotoga maritima], score 147, E-value 1.00E-34.
  
  
 0.627
PepD
Di- and tripeptidases; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
    0.620
Nfo
Endonuclease IV; Best Blastp hit = gi|7450745|pir||G69001 endonuclease IV - Methanobacterium thermoautotrophicum (strain Delta H) gi|2622112|gb|AAB85506.1| (AE000874) endonuclease IV [Methanothermobacter thermautotrophicus], score 183, E-value 3.00E-45.
     
 0.614
PolA
DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
    0.588
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.