STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pgk3-phosphoglycerate kinase; Best Blastp hit = gi|129919|sp|P18912|PGK_BACST PHOSPHOGLYCERATE KINASE gi|80216|pir||JQ1399 phosphoglycerate kinase (EC 2.7.2.3) - Bacillus stearothermophilus gi|576239|pdb|1PHP| 3-Phosphoglycerate Kinase (Pgk) (E.C.2.7.2.3) gi|48855|emb|CAA41093.1| (X58059) 3-phosphoglycerate kinase [Bacillus stearothermophilus], score 509, E-value 1.00E-143. (394 aa)    
Predicted Functional Partners:
Eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.999
TpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
GapA
Best Blastp hit = gi|3915700|sp|P00362|G3P_BACST GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) gi|80204|pir||JS0164 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Bacillus stearothermophilus gi|142952|gb|AAA22461.1| (M24493) glyceraldehyde-3-phosphate dehydrogenase [Bacillus stearothermophilus], score 490, E-value 1.00E-137.
 0.999
GpmA
Phosphoglycerate mutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.983
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
 
 
 0.971
Pgi
Glucose-6-phosphate isomerase; Best Blastp hit = gi|120717|sp|P13375|G6PA_BACST GLUCOSE-6-PHOSPHATE ISOMERASE A (GPI A) (PHOSPHOGLUCOSE ISOMERASE A) (PGI-A) gi|68452|pir||NUBSSA glucose-6-phosphate isomerase (EC 5.3.1.9) A [validated] - Bacillus stearothermophilus gi|40046|emb|CAA34634.1| (X16639) phosphoglucose isomerase A (AA 1-449) [Bacillus stearothermophilus], score 617, E-value 1.00E-176.
  
 
 0.960
Fba
Fructose/tagatose bisphosphate aldolase; Best Blastp hit = gi|6652729|gb|AAF22441.1|AF052204_1 '(AF052204) fructose-1,6-bisphosphate aldolase [Thermus aquaticus]', score 313, E-value 2.00E-84.
  
 
 0.950
PfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
  
 0.835
PorA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
  
 0.824
PolA
DNA polymerase I - 3'-5' exonuclease and polymerase domains; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.762
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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