STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FcbCPredicted thioesterase; Best Blastp hit = gi|13701148|dbj|BAB42443.1| (AP003133) conserved hypothetical protein [Staphylococcus aureus] gi|13875664|dbj|BAB45269.1| (AP003362) conserved hypothetical protein [Staphylococcus aureus], score 93.2, E-value 1.00E-18. (138 aa)    
Predicted Functional Partners:
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
       0.824
PfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
       0.805
TTE1817
Hypothetical protein.
       0.683
FabD
(acyl-carrier-protein) S-malonyltransferase; Best Blastp hit = gi|7404378|sp|P71019|FABD_BACSU MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE (MCT) gi|7433733|pir||H69620 [acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39) fabD [validated] - Bacillus subtilis gi|2337819|emb|CAA74249.1| (Y13937) putative FabD protein [Bacillus subtilis] gi|2633962|emb|CAB13463.1| (Z99112) malonyl CoA-acyl carrier protein transacylase [Bacillus subtilis], score 276, E-value 2.00E-73.
  
 
 0.679
AcpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
 
 0.624
DnaE
DNA polymerase III alpha subunit; Best Blastp hit = gi|3913509|sp|O51526|DP3A_BORBU DNA POLYMERASE III ALPHA SUBUNIT gi|7434830|pir||B70172 'DNA polymerase III, subunit alpha (dnaE) homolog - Lyme disease spirochete' gi|2688500|gb|AAC66944.1| '(AE001159) DNA polymerase III, subunit alpha (dnaE) [Borrelia burgdorferi]', score 914, E-value 0.
       0.605
FliG
Flagellar motor switch protein; Best Blastp hit = gi|10175077|dbj|BAB06176.1| (AP001515) flagellar motor switch protein [Bacillus halodurans], score 454, E-value 1.00E-127.
    
   0.541
TTE1813
Conserved hypothetical protein; Best Blastp hit = gi|231542|sp|P29761|AMYG_CLOSP 'GLUCOAMYLASE PRECURSOR (GLUCAN 1,4-ALPHA-GLUCOSIDASE) (1,4-ALPHA-D-GLUCAN GLUCOHYDROLASE)' gi|98626|pir||JQ0868 'glucan 1,4-alpha-glucosidase (EC 3.2.1.3) precursor - Clostridium sp' gi|216417|dbj|BAA02251.1| (D12818) glucoamylase precursor [Clostridium sp.], score 1044, E-value 0.
       0.516
SecA
Preprotein translocase subunit SecA (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
 
 
   0.502
TTE1819
CBS domains; Best Blastp hit = gi|10175798|dbj|BAB06894.1| (AP001518) BH3175; unknown conserved protein [Bacillus halodurans], score 347, E-value 2.00E-94.
     
 0.478
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.