Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Dak1.2Dihydroxyacetone kinase; Best Blastp hit = gi|10176020|dbj|BAB07116.1| (AP001518) dihydroxyacetone kinase [Bacillus halodurans], score 320, E-value 1.00E-86. (332 aa)    
Predicted Functional Partners:
TTE1995
Conserved hypothetical protein; Best Blastp hit = gi|2506647|sp|P37349|YCGC_ECOLI HYPOTHETICAL 51.6 KDA PROTEIN IN TREA-PTH INTERGENIC REGION gi|7466956|pir||C64866 trehalase precursor - Escherichia coli gi|1787448|gb|AAC74282.1| (AE000218) putative PTS system enzyme I [Escherichia coli K12] gi|4062781|dbj|BAA36055.1| (D90754) Hypothetical protein in treA 5'region. [Escherichia coli], score 80.5, E-value 8.00E-15.
 0.999
Dak1
Dihydroxyacetone kinase; Best Blastp hit = gi|10186493|gb|AAG14892.1|AF297121_5 (AF297121) unknown [Selenomonas ruminantium subsp. ruminantium], score 196, E-value 2.00E-49.
 
 0.999
DeoR
Transcriptional regulator, contains sigma factor-related N-terminal domain; Best Blastp hit = gi|10173394|dbj|BAB04499.1| (AP001509) transcriptional regulator [Bacillus halodurans], score 196, E-value 3.00E-49.
     0.923
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
 
  
 0.896
TTE2001
Predicted dehydrogenase; Best Blastp hit = gi|7462237|pir||E72254 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981997|gb|AAD36502.1|AE001795_5 (AE001795) conserved hypothetical protein [Thermotoga maritima], score 389, E-value 1.00E-107.
    
  0.896
GlpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
     
 0.812
GpsA
Best Blastp hit = gi|7431307|pir||H69636 glycerol-3-phosphate dehydrogenase (NAD+) (EC 1.1.1.8) gpsA - Bacillus subtilis gi|1146220|gb|AAC83967.1| (L47648) NAD+ dependent glycerol-3-phosphate dehydrogenase [Bacillus subtilis] gi|2634701|emb|CAB14199.1| (Z99115) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus subtilis], score 327, E-value 1.00E-88; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
   
 
 0.807
TpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.673
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
      
 0.637
GapA
Best Blastp hit = gi|3915700|sp|P00362|G3P_BACST GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) gi|80204|pir||JS0164 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Bacillus stearothermophilus gi|142952|gb|AAA22461.1| (M24493) glyceraldehyde-3-phosphate dehydrogenase [Bacillus stearothermophilus], score 490, E-value 1.00E-137.
   
  
 0.636
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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