Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
HcaD2Uncharacterized NAD(FAD)-dependent dehydrogenases; Best Blastp hit = gi|7462829|pir||F72254 hypothetical protein TM1433 - Thermotoga maritima (strain MSB8) gi|4981998|gb|AAD36503.1|AE001795_6 '(AE001795) oxidoreductase, putative [Thermotoga maritima]', score 310, E-value 2.00E-83. (419 aa)    
Predicted Functional Partners:
TTE1999
Conserved hypothetical protein; Best Blastp hit = gi|7462675|pir||G72254 hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981999|gb|AAD36504.1|AE001795_7 (AE001795) hypothetical protein [Thermotoga maritima], score 132, E-value 2.00E-30.
    0.996
TTE2001
Predicted dehydrogenase; Best Blastp hit = gi|7462237|pir||E72254 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981997|gb|AAD36502.1|AE001795_5 (AE001795) conserved hypothetical protein [Thermotoga maritima], score 389, E-value 1.00E-107.
  
 0.996
GcvT
Glycine cleavage system T protein (aminomethyltransferase); The glycine cleavage system catalyzes the degradation of glycine.
 
 
  
 0.884
GrxC
Glutaredoxin and related proteins; Best Blastp hit = gi|7451278|pir||F72303 glutaredoxin - Thermotoga maritima (strain MSB8) gi|4981572|gb|AAD36108.1|AE001764_11 (AE001764) glutaredoxin [Thermotoga maritima], score 90.9, E-value 1.00E-17.
  
 
 0.872
GlpP
Glycerol-3-phosphate responsive antiterminator (mRNA-binding); Best Blastp hit = gi|7462400|pir||D72254 glycerol uptake operon antiterminator - Thermotoga maritima (strain MSB8) gi|4981996|gb|AAD36501.1|AE001795_4 (AE001795) glycerol uptake operon antiterminator [Thermotoga maritima], score 165, E-value 3.00E-40.
 
    0.802
AtoC2
AAA superfamily ATPases with N-terminal receiver domain; Best Blastp hit = gi|10176524|dbj|BAB07618.1| (AP001520) transcriptional regulator [Bacillus halodurans], score 311, E-value 1.00E-83.
       0.780
TTE2338
Conserved hypothetical protein; Best Blastp hit = gi|11349142|pir||A83493 hypothetical protein PA1234 [imported] - Pseudomonas aeruginosa (strain PAO1) gi|9947163|gb|AAG04623.1|AE004552_13 (AE004552) hypothetical protein [Pseudomonas aeruginosa], score 55.8, E-value 3.00E-07.
  
 
 0.751
AhpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.665
AhpC2
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 
 0.665
GlpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
       0.602
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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