Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GlpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa)    
Predicted Functional Partners:
GlpF
Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Best Blastp hit = gi|7387712|sp|Q9X1E3|GLPF_THEMA PROBABLE GLYCEROL UPTAKE FACILITATOR PROTEIN gi|7444137|pir||B72254 glycerol uptake facilitator protein - Thermotoga maritima (strain MSB8) gi|4981994|gb|AAD36499.1|AE001795_2 (AE001795) glycerol uptake facilitator protein [Thermotoga maritima], score 289, E-value 3.00E-77; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
 0.988
plsY
Conserved hypothetical protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
    
 0.934
PykF
Pyruvate kinase; Best Blastp hit = gi|10175785|dbj|BAB06882.1| (AP001517) pyruvate kinase [Bacillus halodurans], score 674, E-value 0; Belongs to the pyruvate kinase family.
   
 
 0.835
SpoVK
ATPases of the AAA+ class; Best Blastp hit = gi|98485|pir||S16301 spore formation protein spoVK - Bacillus subtilis gi|40197|emb|CAA42049.1| (X59412) spoVJ [Bacillus subtilis], score 282, E-value 4.00E-75.
   
  0.812
Dak1.2
Dihydroxyacetone kinase; Best Blastp hit = gi|10176020|dbj|BAB07116.1| (AP001518) dihydroxyacetone kinase [Bacillus halodurans], score 320, E-value 1.00E-86.
     
 0.812
Dak1
Dihydroxyacetone kinase; Best Blastp hit = gi|10186493|gb|AAG14892.1|AF297121_5 (AF297121) unknown [Selenomonas ruminantium subsp. ruminantium], score 196, E-value 2.00E-49.
     
 0.799
TpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
  
 0.787
GlpP
Glycerol-3-phosphate responsive antiterminator (mRNA-binding); Best Blastp hit = gi|7462400|pir||D72254 glycerol uptake operon antiterminator - Thermotoga maritima (strain MSB8) gi|4981996|gb|AAD36501.1|AE001795_4 (AE001795) glycerol uptake operon antiterminator [Thermotoga maritima], score 165, E-value 3.00E-40.
  
  
 0.786
GapA
Best Blastp hit = gi|3915700|sp|P00362|G3P_BACST GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) gi|80204|pir||JS0164 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Bacillus stearothermophilus gi|142952|gb|AAA22461.1| (M24493) glyceraldehyde-3-phosphate dehydrogenase [Bacillus stearothermophilus], score 490, E-value 1.00E-137.
   
 
 0.780
PorA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
     
 0.778
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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