Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GlpPGlycerol-3-phosphate responsive antiterminator (mRNA-binding); Best Blastp hit = gi|7462400|pir||D72254 glycerol uptake operon antiterminator - Thermotoga maritima (strain MSB8) gi|4981996|gb|AAD36501.1|AE001795_4 (AE001795) glycerol uptake operon antiterminator [Thermotoga maritima], score 165, E-value 3.00E-40. (189 aa)    
Predicted Functional Partners:
GlpF
Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); Best Blastp hit = gi|7387712|sp|Q9X1E3|GLPF_THEMA PROBABLE GLYCEROL UPTAKE FACILITATOR PROTEIN gi|7444137|pir||B72254 glycerol uptake facilitator protein - Thermotoga maritima (strain MSB8) gi|4981994|gb|AAD36499.1|AE001795_2 (AE001795) glycerol uptake facilitator protein [Thermotoga maritima], score 289, E-value 3.00E-77; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
  
 0.882
TTE1999
Conserved hypothetical protein; Best Blastp hit = gi|7462675|pir||G72254 hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981999|gb|AAD36504.1|AE001795_7 (AE001795) hypothetical protein [Thermotoga maritima], score 132, E-value 2.00E-30.
 
    0.809
HcaD2
Uncharacterized NAD(FAD)-dependent dehydrogenases; Best Blastp hit = gi|7462829|pir||F72254 hypothetical protein TM1433 - Thermotoga maritima (strain MSB8) gi|4981998|gb|AAD36503.1|AE001795_6 '(AE001795) oxidoreductase, putative [Thermotoga maritima]', score 310, E-value 2.00E-83.
 
    0.802
TTE2001
Predicted dehydrogenase; Best Blastp hit = gi|7462237|pir||E72254 conserved hypothetical protein - Thermotoga maritima (strain MSB8) gi|4981997|gb|AAD36502.1|AE001795_5 (AE001795) conserved hypothetical protein [Thermotoga maritima], score 389, E-value 1.00E-107.
 
     0.794
GlpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
  
 0.786
mprF
Predicted integral membrane protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
       0.493
Cda1.3
Predicted xylanase/chitin deacetylase; Best Blastp hit = gi|10173510|dbj|BAB04614.1| (AP001510) polysaccharide deacetylase (nodulation protein NodB) [Bacillus halodurans], score 247, E-value 1.00E-64.
       0.493
TTE1995
Conserved hypothetical protein; Best Blastp hit = gi|2506647|sp|P37349|YCGC_ECOLI HYPOTHETICAL 51.6 KDA PROTEIN IN TREA-PTH INTERGENIC REGION gi|7466956|pir||C64866 trehalase precursor - Escherichia coli gi|1787448|gb|AAC74282.1| (AE000218) putative PTS system enzyme I [Escherichia coli K12] gi|4062781|dbj|BAA36055.1| (D90754) Hypothetical protein in treA 5'region. [Escherichia coli], score 80.5, E-value 8.00E-15.
 
     0.485
PorA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
     
 0.424
Dak1
Dihydroxyacetone kinase; Best Blastp hit = gi|10186493|gb|AAG14892.1|AF297121_5 (AF297121) unknown [Selenomonas ruminantium subsp. ruminantium], score 196, E-value 2.00E-49.
       0.405
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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