STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTE2199Ferredoxin 3; Best Blastp hit = gi|7462853|pir||G72214 hypothetical protein TM1758 - Thermotoga maritima (strain MSB8) gi|4982337|gb|AAD36823.1|AE001814_5 '(AE001814) 2-oxoisovalerate oxidoreductase, gamma subunit, putative [Thermotoga maritima]', score 76.6, E-value 4.00E-14. (70 aa)    
Predicted Functional Partners:
TTE2200
Conserved hypothetical protein; Best Blastp hit = gi|7462621|pir||F72214 hypothetical protein - Thermotoga maritima (strain MSB8) gi|4982336|gb|AAD36822.1|AE001814_4 (AE001814) hypothetical protein [Thermotoga maritima], score 160, E-value 2.00E-38.
 
     0.962
PorA6
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|7433688|pir||H72214 hypothetical protein TM1759 - Thermotoga maritima (strain MSB8) gi|4982338|gb|AAD36824.1|AE001814_6 '(AE001814) 2-oxoisovalerate oxidoreductase, beta subunit, putative [Thermotoga maritima]', score 419, E-value 1.00E-116.
 
 
 0.959
HycE
Ni,Fe-hydrogenase III large subunit; Best Blastp hit = gi|123919|sp|P16431|HYCE_ECOLI FORMATE HYDROGENLYASE SUBUNIT 5 PRECURSOR (FHL SUBUNIT 5) (HYDROGENASE-3 COMPONENT E) gi|78775|pir||S08623 hydrogenase (EC 1.18.99.1) 3 chain 5 precursor - Escherichia coli gi|41684|emb|CAA35550.1| (X17506) hycE [Escherichia coli] gi|882614|gb|AAA69231.1| (U29579) formate hydrogenlyase subunit 5 [Escherichia coli] gi|1789076|gb|AAC75763.1| (AE000356) large subunit of hydrogenase 3 (part of FHL complex) [Escherichia coli K12] gi|1093498|prf||2104213E hycE gene [Escherichia coli], score 755, E-value 0.
  
 
 0.958
Icd
Isocitrate dehydrogenases; Best Blastp hit = gi|7431248|pir||H72288 isocitrate dehydrogenase - Thermotoga maritima (strain MSB8) gi|4981696|gb|AAD36224.1|AE001772_3 (AE001772) isocitrate dehydrogenase [Thermotoga maritima], score 536, E-value 1.00E-151; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 
 0.943
PorA
Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Best Blastp hit = gi|4972241|emb|CAB43935.1| (Y17727) pyruvate ferredoxin oxidoreductase [Clostridium pasteurianum], score 1671, E-value 0; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.938
NuoF
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Best Blastp hit = gi|7431975|pir||D72430 'NADP-reducing hydrogenase, subunit C - Thermotoga maritima (strain MSB8)' gi|4980493|gb|AAD35104.1|AE001689_10 '(AE001689) NADP-reducing hydrogenase, subunit C [Thermotoga maritima]', score 757, E-value 0.
  
 0.920
TTE0126
echD; Best Blastp hit = gi|3005970|emb|CAA76120.1| (Y16191) echD [Methanosarcina barkeri], score 78.2, E-value 4.00E-14.
  
 0.911
NuoE
NADH:ubiquinone oxidoreductase 24 kD subunit; Best Blastp hit = gi|2126446|pir||A57150 NADP-reducing hydrogenase (EC 1.-.-.-) chain A - Desulfovibrio fructosovorans gi|466363|gb|AAA87054.1| (U07229) potential NAD-reducing hydrogenase subunit [Desulfovibrio fructosovorans], score 157, E-value 1.00E-37.
  
 0.900
AcpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
   
 0.867
AspA
Aspartate ammonia-lyase; Best Blastp hit = gi|10174043|dbj|BAB05145.1| (AP001512) aspartate ammonia-lyase [Bacillus halodurans], score 426, E-value 1.00E-118.
   
  0.818
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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