| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GuaA | PrfB | TTE0583 | TTE0523 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.591 |
| GuaA | PrsA | TTE0583 | TTE2571 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.881 |
| GuaA | Pth | TTE0583 | TTE2567 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.779 |
| GuaA | RplY | TTE0583 | TTE1982 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.599 |
| GuaA | ychF | TTE0583 | TTE1658 | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | Predicted GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.802 |
| LytB | Pth | TTE1352 | TTE2567 | Penicillin tolerance protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.728 |
| Mfd | PrfB | TTE2565 | TTE0523 | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.662 |
| Mfd | PrsA | TTE2565 | TTE2571 | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.514 |
| Mfd | Pth | TTE2565 | TTE2567 | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.933 |
| Mfd | SurA2 | TTE2565 | TTE2564 | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Parvulin-like peptidyl-prolyl isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. | 0.732 |
| Mfd | TTE2563 | TTE2565 | TTE2563 | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Transcription regulator spoVT; Best Blastp hit = gi|586883|sp|P37554|SP5T_BACSU STAGE V SPORULATION PROTEIN T gi|2126881|pir||S66086 AbrB homolog - Bacillus subtilis gi|7475924|pir||F69716 transcription regulator spoVT - Bacillus subtilis gi|467445|dbj|BAA05291.1| (D26185) similar to AbrB [Bacillus subtilis] gi|2632323|emb|CAB11832.1| (Z99104) transcriptional regulator [Bacillus subtilis], score 201, E-value 5.00E-51. | 0.709 |
| Mfd | TTE2566 | TTE2565 | TTE2566 | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Hypothetical protein. | 0.842 |
| PrfB | GuaA | TTE0523 | TTE0583 | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.591 |
| PrfB | Mfd | TTE0523 | TTE2565 | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.662 |
| PrfB | Pth | TTE0523 | TTE2567 | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.687 |
| PrfB | RplY | TTE0523 | TTE1982 | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | Ribosomal protein L25 (general stress protein Ctc); This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. | 0.809 |
| PrfB | ychF | TTE0523 | TTE1658 | Protein chain release factor B; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | Predicted GTPase; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.468 |
| PrsA | GuaA | TTE2571 | TTE0583 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | GMP synthase - PP-ATPase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.881 |
| PrsA | Mfd | TTE2571 | TTE2565 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Transcription-repair coupling factor - superfamily II helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.514 |
| PrsA | Pth | TTE2571 | TTE2567 | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | Peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.730 |
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