STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spo0J5Predicted Transcriptional regulator; Best Blastp hit = gi|10176684|dbj|BAB07778.1| (AP001520) DNA-binding protein Spo0J-like homolog [Bacillus halodurans], score 222, E-value 5.00E-57; Belongs to the ParB family. (268 aa)    
Predicted Functional Partners:
Soj
ATPases involved in chromosome partitioning; Best Blastp hit = gi|586852|sp|P37522|SOJ_BACSU SPORULATION INITIATION INHIBITOR PROTEIN SOJ gi|2127177|pir||I40444 Spo0A activation inhibitor soj - Bacillus subtilis gi|467381|dbj|BAA05227.1| (D26185) regulation of Spo0J and Orf283 (probable) [Bacillus subtilis] gi|580906|emb|CAA44408.1| (X62539) unnamed protein product [Bacillus subtilis] gi|2636644|emb|CAB16134.1| (Z99124) soj [Bacillus subtilis], score 318, E-value 4.00E-86.
 
 0.990
Spo0J4
Predicted Transcriptional regulator; Best Blastp hit = gi|10176682|dbj|BAB07776.1| (AP001520) stage 0 sporulation protein J [Bacillus halodurans], score 268, E-value 5.00E-71; Belongs to the ParB family.
 
   
0.875
GidB
Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.720
Spo0J
Predicted Transcriptional regulator; Best Blastp hit = gi|12230456|sp|Q9KNG7|PARB_VIBCH PROBABLE CHROMOSOME PARTITIONING PROTEIN PARB gi|11280351|pir||D82035 ParB family protein VC2772 [imported] - Vibrio cholerae (group O1 strain N16961) gi|9657374|gb|AAF95911.1| (AE004343) ParB family protein [Vibrio cholerae], score 64.7, E-value 2.00E-09.
  
     0.661
FtsK
DNA segregation ATPase FtsK/SpoIIIE and related proteins; Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity). Belongs to the FtsK/SpoIIIE/SftA family.
  
  
 0.642
TTE2200
Conserved hypothetical protein; Best Blastp hit = gi|7462621|pir||F72214 hypothetical protein - Thermotoga maritima (strain MSB8) gi|4982336|gb|AAD36822.1|AE001814_4 (AE001814) hypothetical protein [Thermotoga maritima], score 160, E-value 2.00E-38.
  
 
 0.633
TTE1111
Glucose-inhibited division protein; Best Blastp hit = gi|11132401|sp|Q9K5M8|GIDB_BACHD GLUCOSE INHIBITED DIVISION PROTEIN B gi|10176685|dbj|BAB07779.1| (AP001520) glucose-inhibited division protein [Bacillus halodurans], score 83.2, E-value 6.00E-16.
  
  
 0.607
TTE2788
Hypothetical protein.
  
 
 0.606
MutT4
NTP pyrophosphohydrolases including oxidative damage repair enzymes; Best Blastp hit = gi|2641974|dbj|BAA23614.1| (AB005149) orf2 [Exiguobacterium acetylicum], score 64.7, E-value 6.00E-10.
       0.592
YidC
Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity).
 
    0.571
Your Current Organism:
Caldanaerobacter subterraneus
NCBI taxonomy Id: 273068
Other names: C. subterraneus subsp. tengcongensis MB4, Caldanaerobacter subterraneus subsp. tengcongensis MB4, Thermoanaerobacter tengcongensis MB4, Thermoanaerobacter tengcongensis str. MB4, Thermoanaerobacter tengcongensis strain MB4
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