STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0066Similarity to known protein: Flavobacterium johnsoniae gliding motility protein (gldA) gene, completecds; and unknown genes; TREMBL:AF007381_3. (260 aa)    
Predicted Functional Partners:
Ta0087
Similarity to unknown protein: hypothetical protein PH1365 - Pyrococcus horikoshii; PIR:G71008.
  
 
 0.652
Ta0734
Conserved hypothetical membrane protein; Weak similarity to known protein.
  
 
 0.652
Ta0856
Hypothetical membrane protein.
  
 
 0.652
Ta0065
Similarity to unknown protein: hypothetical protein PAB1697 - Pyrococcus abyssi (strain Orsay); PIR:G75077.
       0.610
Ta0067
Similarity to unknown protein: hypothetical protein PAB1273 - Pyrococcus abyssi (strain Orsay); PIR:E75012.
 
 
   0.579
Ta0870
Similarity to unknown protein: probable membrane protein APE2578 - Aeropyrum pernix (strain K1); PIR:C72492.
 
  
 0.498
Ta0064
Similarity to known protein: acylphosphatase (EC 3.6.1.7) Ch2, skeletal muscle - chicken; PIR:QPCH2Function: Glycolysis / Gluconeogenesis, Phenylalanine metabolism, Pyruvate metabolism.
       0.480
Ta0063
DNA topoisomerase III beta related protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, [...]
       0.477
Ta0062
Similarity to unknown protein: conserved hypothetical protein AF1952 - Archaeoglobus fulgidus; PIR:G69493.
       0.471
Ta1268
Probable 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
 
   0.450
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.