STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0330threonine--tRNA ligase related protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (660 aa)    
Predicted Functional Partners:
Ta1249
Ribosomal protein L15 related protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.988
Ta1131
Strong similarity to known protein: 40s ribosomal protein s13 - fission yeast (Schizosaccharomyces pombe); PIR:S26296.
  
 
 0.981
Ta1112
Translation initiation factor IF-2 related protein; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 (By similarity).
 
 0.967
Ta0361
Probable 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
 
 
 0.963
Ta1257
Probable 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
   
 
 0.957
Ta1271
50S ribosomal protein L3 related protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.932
Ta1266
Probable 50S ribosomal protein L22; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
   
 
 0.919
Ta0099
Probable histidyl-tRNA synthetase; Strong similarity to known protein: Arabidopsis thaliana histidyl-tRNA synthetase mRNA, complete cds; TREMBL:AF020715_1; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.910
Ta0360
Probable 50S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 
 0.895
Ta0639
Similarity to known protein: phenylalanine--tRNA ligase (EC 6.1.1.20) beta chain, cytosolic [validated] - yeast (Saccharomyces cerevisiae); PIR:YFBYAC; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
 
 
 0.891
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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