STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0399Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (179 aa)    
Predicted Functional Partners:
Ta0006
Vacuolar proton-ATPase subunit D related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.952
Ta0433
Probable 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.948
Ta0004
Probable ATP synthase, subunit A (intein containing); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit; Belongs to the ATPase alpha/beta chains family.
   
 
 0.944
Ta0005
Probable ATP synthase (subunit B); Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.
   
 
 0.940
Ta1045
Similarity to known protein: PLASMA MEMBRANE ATPASE 3 (EC 3.6.1.35) (PROTON PUMP).PLASMA MEMBRANE ATPASE 3 (EC 3.6.1.35) (PROTON PUMP 3) - Arabidopsis thaliana (Mouse-ear cress).Arabidopsis thaliana (Mouse-ear cress); SWISSPROT:PMA3_ARATH.
  
 
 0.923
Ta0008
A1AO H+ ATPase, subunit I related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.921
Ta1059
Translation initiation factor eIF-5a related protein; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
   
  
 0.918
Ta0001
ATP synthase (subunit E) related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 
 
  0.915
Ta0003
ATP synthase(subunit F) related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
  0.912
Ta0002
ATP synthase (subunit C) related protein; Produces ATP from ADP in the presence of a proton gradient across the membrane.
     
  0.900
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.