STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ta0443Molybdopterin biosynthesis protein moaA related protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (324 aa)    
Predicted Functional Partners:
Ta0492
Molybdopterin biosynthesis protein MoaC related protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
 
 0.999
Ta0423
Conserved hypothetical protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
  
 0.923
Ta1023
Similarity to known protein: molybdopterin biosynthesis protein moeA - Escherichia coli; PIR:A32352.
 
 0.910
Ta1480
Similarity to known protein: Homo sapiens molybdopterin-synthase small and large subunit (MOCS2)bicistronic mRNA, complete cds; TREMBL:AF091871_2.
 
  
 0.905
Ta1014
Probable GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
    
  0.902
Ta1138
Conserved hypothetical protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
    
  0.900
Ta0493
Similarity to known protein: MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN B - Escherichia coli; SWISSPROT:MOAB_ECOLI.
 
  
 0.823
Ta1022
Similarity to known protein: MOLYBDOPTERIN BIOSYNTHESIS CNX1 PROTEIN (MOLYBDENUM COFACTORBIOSYNTHESIS ENZYME CNX1) - Arabidopsis thaliana (Mouse-ear cress); SWISSPROT:CNX1_ARATH.
 
 0.817
Ta0896
Similarity to known protein: pyruvate kinase (EC 2.7.1.40) [validated] - Bacillus licheniformis; PIR:JC4220.
    
  0.801
Ta1113
Probable nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.801
Your Current Organism:
Thermoplasma acidophilum
NCBI taxonomy Id: 273075
Other names: T. acidophilum DSM 1728, Thermoplasma acidophilum DSM 1728
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